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Section |
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Reads can naturally overlap one or multiple adjacent exonic segments , i.e. to edges edges such that . To this end we extend E by corresponding super-edges se conflating the attributes of atomary exon segments, and apply Definition 2 without loss of generality. Note that in the case of split-mappings, exonic segments represented by super-edges can be separated by intermediate intronic edges. Paired-end reads are mapped jointly to super-edges that combine the exonic regions to which each mate is mapping, which in turn can be already super-edges (Fig.2). |
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