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  • 4.3.1 - RNA Hydrolysis

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Second,  breakpoints are sampled uniformly from the interval [0;1[, resulting in relative length fractions  for all  fragments. Third, relative fragment sizes  are transformed from unit space to sizes  that follow a Weibull distribution of shape  by:


where  is a constant of the transformation to ensure that the sizes of the  fragments sum up exactly to the given molecule length. Latter transformation produces a slightly distorted Weibull distribution for the sizes , however the deviation is sufficiently small to be neglected in our applications.