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Similar to the concept of splicing graphs [Heber 2002], we employ a graph structure G=(V,E) for representing the reference transcriptome that is quantified in a non-redundant data structure. Each edge e=(tail,head,mode,T) represents a segment of an annotated pre-mRNA molecule by the genomic coordinate of the corresponding 3'-tail and 5'-head position, by the type (exonic or intronic), and by the set T of supporting transcripts (Lemma 1).